Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | PLK4 | O00444 | 2/20 | 0.41 |
| ▸ | PAK4 | O96013 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28412117 | 1.00 | AXL (0.42) | AXLMKNK1BRD4PLK4PAK4 | |
| SCHEMBL31749129 | 0.83 | PLK4 (0.40) | MKNK1BRD4PLK4PAK4ALDH1A1 | |
| SCHEMBL20389659 | 0.77 | PLK4 (0.48) | PLK4PAK4KDM4EALDH1A1LMNA | |
| SCHEMBL29882851 | 0.77 | PLK4 (0.48) | PLK4PAK4KDM4EALDH1A1LMNA | |
| SCHEMBL30468605 | 0.76 | PLK4 (0.43) | PLK4PAK4RET | |
| SCHEMBL561294 | 0.76 | PLK4 (0.43) | PLK4PAK4RET | |
| SCHEMBL14767818 | 0.74 | KDM4E (0.55) | PLK4PAK4MEN1KMT2AKDM4E | |
| SCHEMBL31555833 | 0.73 | PLK4 (0.41) | AXLPLK4PAK4 | |
| SCHEMBL22554143 | 0.73 | PLK4 (0.41) | PLK4PAK4RET | |
| SCHEMBL22554243 | 0.72 | PLK4 (0.38) | AXLMKNK1BRD4PLK4PAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025264959-A1 | SUBSTITUTED PYRAZOLOPYRIDINES AS PHOSPHOINOSIDIDE KINASE (PIK) MODULATORS | RECURSION PHARMACEUTICALS, INC. (US) | 2025-12-26 | — | — | WO | disclosed |
| CN-111153899-B | Substituted pyridine compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-12-01 | — | — | CN | disclosed |