SCHEMBL30683149

SCHEMBL30683149

Sc1c(Br)cc(Br)c(Br)c1Br

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.40
CA2 P00918 2/20 0.39
CA4 P22748 2/20 0.39
CA1 P00915 1/20 0.39
CA6 P23280 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
AKR1B1 P15121 2/20 0.33
EIF2AK2 P19525 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
CSNK2A1 P68400 1/20 0.32
AHR P35869 2/20 0.32
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6513036 1.00 APEX1 (0.40) APEX1CA2CA4CA1CA6
SCHEMBL6512403 0.97 APEX1 (0.38) APEX1CA2CA4CA1CA6
SCHEMBL6512410 0.97 APEX1 (0.38) APEX1CA2CA4CA1CA6
SCHEMBL6515891 0.97 APEX1 (0.38) APEX1CA2CA4CA1CA6
SCHEMBL10966591 0.81 APEX1 (0.40) APEX1CA2CA4CA1CA6
SCHEMBL48236 0.80 APEX1 (0.44) APEX1CA2CA4CA1CA6
SCHEMBL331038 0.79 APEX1 (0.38) APEX1CA2CA4CA1CA6
Ethylene SCHEMBL3851523 0.69 TDP1 (0.50) APEX1CA2CA4CA1CA6
Ethane SCHEMBL27516377 0.69 TDP1 (0.50) APEX1CA2CA4CA1CA6
Ethylene SCHEMBL27257227 0.69 TDP1 (0.50) APEX1CA2CA4CA1CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230390610-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2023-12-07 US disclosed