Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CGAS | Q8N884 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 2/20 | 0.31 |
| ▸ | SGK1 | O00141 | 1/20 | 0.31 |
| ▸ | CDC42BPB | Q9Y5S2 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26912152 | 1.00 | CGAS (0.37) | CGASROCK2ROCK1PIK3CALRRK2 | |
| SCHEMBL26912204 | 1.00 | CGAS (0.37) | CGASROCK2ROCK1PIK3CALRRK2 | |
| SCHEMBL26912151 | 1.00 | CGAS (0.37) | CGASROCK2ROCK1PIK3CALRRK2 | |
| SCHEMBL30684264 | 0.94 | CGAS (0.36) | CGASROCK2ROCK1PIK3CALRRK2 | |
| SCHEMBL26912218 | 0.94 | CGAS (0.36) | CGASROCK2ROCK1PIK3CALRRK2 | |
| SCHEMBL26912225 | 0.94 | CGAS (0.36) | CGASROCK2ROCK1PIK3CALRRK2 | |
| SCHEMBL26912468 | 0.85 | CGAS (0.34) | CGASROCK2ROCK1LRRK2CDC42BPB | |
| SCHEMBL26912472 | 0.85 | CGAS (0.34) | CGASROCK2ROCK1LRRK2CDC42BPB | |
| SCHEMBL26912777 | 0.84 | CGAS (0.35) | CGASROCK2ROCK1CDC42BPB | |
| SCHEMBL26913188 | 0.84 | LRRK2 (0.35) | CGASROCK2ROCK1LRRK2CDC42BPB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235809-A1 | CGAS INHIBITORS | ELI LILLY AND COMPANY (US) | 2023-12-07 | — | — | WO | disclosed |