Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 2/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26913324 | 1.00 | KDM5B (0.33) | KDM5BFGFR1P2RY12FLT3FGFR2 | |
| SCHEMBL26912583 | 1.00 | KDM5B (0.33) | KDM5BFGFR1P2RY12FLT3FGFR2 | |
| SCHEMBL30684321 | 1.00 | KDM5B (0.33) | KDM5BFGFR1P2RY12FLT3FGFR2 | |
| SCHEMBL30684306 | 0.92 | KDM5B (0.32) | KDM5BFGFR1FLT3FGFR2FGFR4 | |
| SCHEMBL26912865 | 0.92 | KDM5B (0.32) | KDM5BFGFR1FLT3FGFR2FGFR4 | |
| SCHEMBL30684276 | 0.92 | KDM5B (0.32) | KDM5BFGFR1FLT3FGFR2FGFR4 | |
| SCHEMBL26912365 | 0.92 | KDM5B (0.32) | KDM5BFGFR1FLT3FGFR2FGFR4 | |
| SCHEMBL26912631 | 0.88 | KDM5B (0.33) | KDM5BFGFR1FLT3FGFR2FGFR4 | |
| SCHEMBL30684418 | 0.85 | KDM5B (0.31) | KDM5BFGFR1 | |
| SCHEMBL26913756 | 0.85 | KDM5B (0.31) | KDM5BFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235809-A1 | CGAS INHIBITORS | ELI LILLY AND COMPANY (US) | 2023-12-07 | — | — | WO | disclosed |