Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26912783 | 1.00 | PDE4A (0.33) | PDE4AROCK2ROCK1EZH2 | |
| SCHEMBL26912609 | 0.91 | EZH2 (0.32) | ROCK2ROCK1EZH2 | |
| SCHEMBL30684427 | 0.91 | EZH2 (0.32) | ROCK2ROCK1EZH2 | |
| Hydrochloric Acid SCHEMBL26913319 | 0.81 | PDE4A (0.37) | PDE4AROCK2EZH2 | |
| SCHEMBL30684343 | 0.78 | EZH2 (0.34) | EZH2 | |
| SCHEMBL26913942 | 0.78 | EZH2 (0.34) | EZH2 | |
| SCHEMBL26912868 | 0.77 | CREBBP (0.34) | — | |
| Hydrochloric Acid SCHEMBL30684438 | 0.75 | PDE4A (0.40) | PDE4AROCK2EZH2 | |
| SCHEMBL30684229 | 0.75 | CGAS (0.44) | ROCK2ROCK1 | |
| SCHEMBL26912473 | 0.75 | CGAS (0.44) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235809-A1 | CGAS INHIBITORS | ELI LILLY AND COMPANY (US) | 2023-12-07 | — | — | WO | disclosed |