Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CGAS | Q8N884 | 3/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.31 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | BUB1 | O43683 | 1/20 | 0.30 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26913300 | 1.00 | CGAS (0.36) | CGASROCK2ROCK1EZH2GRM2 | |
| SCHEMBL30684437 | 0.86 | CGAS (0.36) | CGASEZH2GRM2 | |
| SCHEMBL26912898 | 0.86 | CGAS (0.36) | CGASEZH2GRM2 | |
| SCHEMBL26913043 | 0.82 | CGAS (0.33) | CGASROCK2ROCK1EZH2GRM2 | |
| SCHEMBL30684317 | 0.82 | CGAS (0.33) | CGASROCK2ROCK1EZH2GRM2 | |
| SCHEMBL26912442 | 0.80 | CGAS (0.33) | CGASEZH2 | |
| SCHEMBL30684432 | 0.80 | CGAS (0.33) | CGASEZH2 | |
| Hydrochloric Acid SCHEMBL26913814 | 0.79 | GRM2 (0.34) | CGASEZH2GRM2PDE4A | |
| Hydrochloric Acid SCHEMBL30684428 | 0.79 | GRM2 (0.34) | CGASEZH2GRM2PDE4A | |
| SCHEMBL30684384 | 0.77 | EZH2 (0.35) | EZH2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235809-A1 | CGAS INHIBITORS | ELI LILLY AND COMPANY (US) | 2023-12-07 | — | — | WO | disclosed |