Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CGAS | Q8N884 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 3/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26913797 | 1.00 | CGAS (0.39) | CGASPIM1PGK1NTRK1LRRK2 | |
| SCHEMBL26913181 | 0.81 | CGAS (0.39) | CGASPIM1LRRK2 | |
| SCHEMBL26912287 | 0.76 | CGAS (0.41) | CGASPIM1 | |
| SCHEMBL30684371 | 0.75 | PIM1 (0.34) | CGASPIM1PGK1NTRK1LRRK2 | |
| SCHEMBL26913265 | 0.75 | PIM1 (0.34) | CGASPIM1PGK1NTRK1LRRK2 | |
| SCHEMBL26912304 | 0.72 | FEN1 (0.34) | CGASPIM1LRRK2 | |
| SCHEMBL26912495 | 0.70 | CGAS (0.33) | CGAS | |
| SCHEMBL30684349 | 0.69 | CGAS (0.39) | CGASNTRK1 | |
| SCHEMBL26913442 | 0.69 | CGAS (0.39) | CGASNTRK1 | |
| SCHEMBL26912713 | 0.69 | CGAS (0.34) | CGASPGK1NTRK1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235809-A1 | CGAS INHIBITORS | ELI LILLY AND COMPANY (US) | 2023-12-07 | — | — | WO | disclosed |