Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 10/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26912807 | 1.00 | MAPK1 (0.38) | MAPK1NTRK1ROCK1MYLK4ROCK2 | |
| SCHEMBL26913442 | 0.84 | CGAS (0.39) | MAPK1NTRK1ROCK1ROCK2IRAK4 | |
| SCHEMBL30684349 | 0.84 | CGAS (0.39) | MAPK1NTRK1ROCK1ROCK2IRAK4 | |
| SCHEMBL26913242 | 0.82 | CGAS (0.38) | ROCK1MYLK4ROCK2IRAK4CGAS | |
| SCHEMBL26912712 | 0.78 | CGAS (0.39) | ROCK1MYLK4ROCK2IRAK4CGAS | |
| SCHEMBL26912544 | 0.76 | CGAS (0.38) | ROCK1MYLK4ROCK2IRAK4CGAS | |
| SCHEMBL26913157 | 0.75 | CGAS (0.35) | ROCK1MYLK4ROCK2CGAS | |
| SCHEMBL26912713 | 0.75 | CGAS (0.34) | NTRK1CGAS | |
| SCHEMBL30684371 | 0.73 | PIM1 (0.34) | MAPK1NTRK1CGAS | |
| SCHEMBL26913265 | 0.73 | PIM1 (0.34) | MAPK1NTRK1CGAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235809-A1 | CGAS INHIBITORS | ELI LILLY AND COMPANY (US) | 2023-12-07 | — | — | WO | disclosed |