Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK4 | O96013 | 13/20 | 0.87 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.59 |
| ▸ | KDR | P35968 | 3/20 | 0.54 |
| ▸ | CSF1R | P07333 | 2/20 | 0.54 |
| ▸ | RET | P07949 | 2/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.54 |
| ▸ | SRC | P12931 | 2/20 | 0.54 |
| ▸ | FLT1 | P17948 | 2/20 | 0.54 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | FLT4 | P35916 | 2/20 | 0.54 |
| ▸ | FLT3 | P36888 | 2/20 | 0.54 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30685852 | 0.77 | PDGFRB (0.68) | PAK4PDGFRAKDRCSF1RRET | |
| SCHEMBL26307535 | 0.76 | GRK5 (0.76) | PAK4 | |
| SCHEMBL30685892 | 0.75 | PDGFRA (0.71) | PAK4PDGFRAKDRCSF1RRET | |
| SCHEMBL12473994 | 0.75 | PDGFRA (1.00) | PAK4PDGFRAKDRCSF1RRET | |
| SCHEMBL12473996 | 0.75 | PDGFRA (1.00) | PAK4PDGFRAKDRCSF1RRET | |
| SCHEMBL5361474 | 0.74 | TLK2 (0.70) | PAK4PDGFRAKDRCSF1RRET | |
| SCHEMBL30685881 | 0.74 | KDR (0.53) | PAK4PDGFRAKDRCSF1RRET | |
| SCHEMBL5368286 | 0.74 | PAK4 (0.69) | PAK4PDGFRAKDRCSF1RRET | |
| SCHEMBL30685781 | 0.74 | PDGFRA (0.58) | PAK4PDGFRAKDRCSF1RRET | |
| SCHEMBL8211131 | 0.73 | RET (0.73) | PDGFRAKDRCSF1RRETFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447455-A | Nitrogen-containing heterocyclic compound | 首药控股(北京)股份有限公司 | 2024-01-26 | — | — | CN | disclosed |