Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.70 |
| ▸ | KDR | P35968 | 5/20 | 0.61 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.61 |
| ▸ | RET | P07949 | 11/20 | 0.60 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.60 |
| ▸ | PAK4 | O96013 | 1/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.58 |
| ▸ | FLT3 | P36888 | 4/20 | 0.58 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.58 |
| ▸ | CSF1R | P07333 | 2/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.56 |
| ▸ | SRC | P12931 | 2/20 | 0.56 |
| ▸ | FLT1 | P17948 | 2/20 | 0.56 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | FLT4 | P35916 | 2/20 | 0.56 |
| ▸ | ABL1 | P00519 | 2/20 | 0.56 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30685885 | 0.84 | PDGFRA (0.53) | TLK2KDRPDPK1RETPDGFRB | |
| SCHEMBL30685881 | 0.83 | KDR (0.53) | TLK2KDRPDPK1RETPDGFRB | |
| SCHEMBL30685781 | 0.83 | PDGFRA (0.58) | TLK2KDRPDPK1RETPDGFRB | |
| SCHEMBL16568378 | 0.82 | TLK2 (0.82) | TLK2KDRPDPK1RETPDGFRB | |
| SCHEMBL14519103 | 0.82 | TLK2 (0.82) | TLK2KDRPDPK1RETPDGFRB | |
| SCHEMBL5369648 | 0.80 | TLK2 (0.74) | TLK2KDRPDPK1RETPDGFRB | |
| SCHEMBL5362637 | 0.80 | TLK2 (0.77) | TLK2KDRPDPK1RETPDGFRB | |
| SCHEMBL5367740 | 0.78 | TLK2 (0.75) | TLK2KDRPDPK1RETPDGFRB | |
| SCHEMBL5364424 | 0.78 | KDR (0.72) | TLK2KDRPDPK1RETPDGFRB | |
| SCHEMBL30685915 | 0.77 | KDR (0.70) | TLK2KDRPDPK1RETPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447455-A | Nitrogen-containing heterocyclic compound | 首药控股(北京)股份有限公司 | 2024-01-26 | — | — | CN | disclosed |