Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 18/20 | 0.84 |
| ▸ | CDK12 | Q9NYV4 | 18/20 | 0.84 |
| ▸ | CCNT1 | O60563 | 17/20 | 0.84 |
| ▸ | CDK9 | P50750 | 17/20 | 0.84 |
| ▸ | CCNE1 | P24864 | 14/20 | 0.84 |
| ▸ | CDK2 | P24941 | 14/20 | 0.84 |
| ▸ | CDK7 | P50613 | 9/20 | 0.84 |
| ▸ | CCNH | P51946 | 9/20 | 0.84 |
| ▸ | MNAT1 | P51948 | 6/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25599168 | 0.92 | CCNK (1.00) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL24588157 | 0.92 | CCNK (1.00) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL22115127 | 0.92 | CCNK (1.00) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL24588204 | 0.91 | CCNK (0.84) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL29492544 | 0.89 | CCNT1 (0.73) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL24588842 | 0.87 | CCNT1 (0.73) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL24588064 | 0.87 | CCNK (0.73) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL29492532 | 0.87 | CCNT1 (0.71) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL29498413 | 0.87 | CCNK (0.77) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL26627022 | 0.87 | CCNT1 (0.72) | CCNKCDK12CCNT1CDK9CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447520-A | Benzo ring substituted pyrimidine compound and application thereof | 广州利弗克医药科技有限公司 | 2024-01-26 | — | — | CN | disclosed |