SCHEMBL30686905

SCHEMBL30686905

CNC(=O)c1csc2c(C(F)(F)F)cc(N3CCC(OC(=O)N[C@@H](C)COC(F)(F)F)CC3)nc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UGT8 Q16880 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21862452 1.00 UGT8 (1.00) UGT8
SCHEMBL21813755 0.92 UGT8 (0.88) UGT8
SCHEMBL21813758 0.92 UGT8 (0.88) UGT8
SCHEMBL21813783 0.92 UGT8 (0.88) UGT8
SCHEMBL21862438 0.92 UGT8 (1.00) UGT8
SCHEMBL21862132 0.91 UGT8 (0.83) UGT8
SCHEMBL21813665 0.90 UGT8 (0.85) UGT8
SCHEMBL21813663 0.90 UGT8 (0.85) UGT8
SCHEMBL21814089 0.90 UGT8 (1.00) UGT8
SCHEMBL21813951 0.89 UGT8 (0.83) UGT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4714447-A1 DRUG COMBINATIONS OF BCL-XL INHIBITORS FOR TREATMENT OF CANCER Stichting Amsterdam UMC (NL) 2026-03-25 EP disclosed
EP-4537114-A1 METHODS FOR THE DETECTION AND TREATMENT OF CANCER Board of Regents, The University of Texas System (US) 2025-04-16 EP disclosed
WO-2023240070-A1 METHODS FOR THE DETECTION AND TREATMENT OF CANCER BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-12-14 WO disclosed