Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12002951 | 0.85 | HRH3 (0.44) | HRH3RECQLMAPK1JAK2JAK1 | |
| SCHEMBL20918704 | 0.82 | HRH3 (0.42) | HRH3RECQLMAPK1JAK2JAK1 | |
| SCHEMBL2633813 | 0.82 | HRH3 (0.42) | HRH3MAPK1JAK2JAK1GAA | |
| SCHEMBL2223446 | 0.81 | HRH3 (0.41) | HRH3MAPK1GAAMEN1ALDH1A1 | |
| SCHEMBL31333761 | 0.81 | HRH3 (0.41) | HRH3RECQLMAPK1JAK2JAK1 | |
| SCHEMBL23945869 | 0.79 | HRH3 (0.40) | HRH3MAPK1JAK2JAK1MEN1 | |
| SCHEMBL30525657 | 0.79 | HRH3 (0.39) | HRH3RECQLMAPK1MEN1KMT2A | |
| SCHEMBL22629968 | 0.78 | CYP2C19 (0.45) | HRH3MAPK1JAK2JAK1SMN1; SMN2 | |
| SCHEMBL1295721 | 0.77 | HRH3 (0.51) | HRH3RECQLMAPK1GAASMN1; SMN2 | |
| SCHEMBL186721 | 0.77 | HRH3 (0.51) | HRH3RECQLMAPK1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247395-A | PDE4B inhibitors | 武汉人福创新药物研发中心有限公司 | 2023-12-19 | — | — | CN | disclosed |