Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | UBE2N | P61088 | 1/20 | 0.60 |
| ▸ | HTR6 | P50406 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29111249 | 1.00 | KDM4E (0.60) | KDM4EUBE2NHTR6L3MBTL1CNR2 | |
| SCHEMBL2134631 | 0.82 | KDM4E (0.67) | KDM4EUBE2NHTR6L3MBTL1ALDH1A1 | |
| SCHEMBL29111231 | 0.81 | KDM4E (0.60) | KDM4EUBE2NHTR6L3MBTL1CNR2 | |
| SCHEMBL30689048 | 0.81 | KDM4E (0.60) | KDM4EUBE2NHTR6L3MBTL1CNR2 | |
| SCHEMBL6798902 | 0.80 | KDM4E (0.64) | KDM4EUBE2NHTR6L3MBTL1ALDH1A1 | |
| SCHEMBL946840 | 0.79 | KDM4E (0.67) | KDM4EUBE2NHTR6L3MBTL1ALDH1A1 | |
| SCHEMBL945912 | 0.79 | KDM4E (0.67) | KDM4EUBE2NHTR6L3MBTL1ALDH1A1 | |
| SCHEMBL6625206 | 0.78 | KDM4E (0.65) | KDM4EUBE2NHTR6L3MBTL1ALDH1A1 | |
| SCHEMBL30689065 | 0.77 | CNR2 (0.42) | KDM4EUBE2NL3MBTL1CNR2ALDH1A1 | |
| SCHEMBL4776849 | 0.77 | KDM4E (0.64) | KDM4EUBE2NHTR6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024326-A | 5-amino substituted indole compound, preparation method thereof and application thereof in anti-acetylcholinesterase medicine | 平顶山学院 | 2023-11-10 | — | — | CN | claimed |
| CN-117024326-A | 5-amino substituted indole compound, preparation method thereof and application thereof in anti-acetylcholinesterase medicine | 平顶山学院 | 2023-11-10 | — | — | CN | disclosed |