Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.33 |
| ▸ | ADRB3 known ✓ | P13945 | 1/20 | 0.33 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | LPL | P06858 | 3/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL38663385 | 1.00 | KCNH2 (0.46) | KCNH2HRH4HRH3LPLLIPG | |
| SCHEMBL2696234 | 0.98 | KCNH2 (0.47) | KCNH2HRH4HRH3LPLLIPG | |
| SCHEMBL2697904 | 0.98 | KCNH2 (0.47) | KCNH2HRH4HRH3LPLLIPG | |
| SCHEMBL28061446 | 0.98 | KCNH2 (0.47) | KCNH2HRH4HRH3LPLLIPG | |
| SCHEMBL2695561 | 0.98 | KCNH2 (0.47) | KCNH2HRH4HRH3LPLLIPG | |
| SCHEMBL674217 | 0.98 | KCNH2 (0.47) | KCNH2HRH4HRH3LPLLIPG | |
| SCHEMBL2696007 | 0.98 | KCNH2 (0.47) | KCNH2HRH4HRH3LPLLIPG | |
| SCHEMBL31554343 | 0.98 | KCNH2 (0.47) | KCNH2HRH4HRH3LPLLIPG | |
| SCHEMBL2697514 | 0.98 | KCNH2 (0.47) | KCNH2HRH4HRH3LPLLIPG | |
| SCHEMBL675808 | 0.98 | KCNH2 (0.47) | KCNH2HRH4HRH3LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117209430-B | Strong hydrophobic alkaline ionic liquid, preparation method and application thereof in tert-butyl hydroperoxide deacidification | 万华化学集团股份有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-117209430-A | Strong hydrophobic alkaline ionic liquid, preparation method and application thereof in tert-butyl hydroperoxide deacidification | 万华化学集团股份有限公司 | 2023-12-12 | — | — | CN | disclosed |