Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30689440 | 0.87 | GSTP1 (0.40) | KMT2ALMNAPKMHDAC1HDAC8 | |
| SCHEMBL23578443 | 0.78 | TP53 (0.45) | LMNAHDAC1HDAC8HDAC2FFAR1 | |
| SCHEMBL31527898 | 0.78 | S1PR1 (0.45) | KMT2ALMNAPKMHDAC1HDAC8 | |
| SCHEMBL30689347 | 0.77 | IP6K1 (0.48) | LMNAFFAR1GSTP1ALDH1A1TSHR | |
| SCHEMBL23578418 | 0.77 | SMN1; SMN2 (0.43) | LMNAHDAC1HDAC8HDAC2GSTP1 | |
| SCHEMBL31527827 | 0.75 | TP53 (0.46) | LMNAFFAR1GSTP1MAPTALDH1A1 | |
| SCHEMBL30689333 | 0.75 | GSTP1 (0.43) | LMNAHDAC1HDAC8HDAC2FFAR1 | |
| SCHEMBL23578048 | 0.75 | HDAC2 (0.43) | LMNAHDAC1HDAC8HDAC2HDAC4 | |
| SCHEMBL25252400 | 0.75 | HDAC8 (0.41) | LMNAHDAC1HDAC8HDAC2MAPT | |
| SCHEMBL23578022 | 0.74 | S1PR4 (0.51) | HDAC1HDAC8HDAC2FFAR1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543875-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | Sitryx Therapeutics Limited (GB) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023247958-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | SITRYX THERAPEUTICS LIMITED (GB) | 2023-12-28 | — | — | WO | disclosed |