SCHEMBL30689337

SCHEMBL30689337

N#Cc1ccc(Oc2ccccn2)cc1Cl

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.56
SLC22A12 Q96S37 15/20 0.54
CYP11B2 P19099 1/20 0.45
MRGPRX4 Q96LA9 1/20 0.41
CYP19A1 P11511 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27368556 1.00 AR (0.56) ARSLC22A12CYP11B2MRGPRX4CYP19A1
SCHEMBL30689410 0.82 DRD1 (0.46) ARSLC22A12MRGPRX4CYP19A1
SCHEMBL30689432 0.82 SLC22A12 (0.43) SLC22A12CYP11B2CYP19A1
SCHEMBL31527990 0.82 CYP19A1 (0.41) ARSLC22A12CYP19A1
SCHEMBL30689416 0.79 AR (0.59) AR
SCHEMBL30689369 0.79 HRH3 (0.39) ARSLC22A12CYP19A1
SCHEMBL4184922 0.78 AR (0.65) ARSLC22A12MRGPRX4CYP19A1
SCHEMBL7074436 0.77 AR (0.47) ARSLC22A12
SCHEMBL18331713 0.77 BACE1 (0.43)
SCHEMBL25955953 0.77 DRD1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119968366-A Oxadiazole derivatives, methods of preparation and use thereof in the treatment of inflammatory diseases 西特瑞治疗有限公司 2025-05-09 CN disclosed
EP-4543875-A1 OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES Sitryx Therapeutics Limited (GB) 2025-04-30 EP disclosed
WO-2023247958-A1 OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES SITRYX THERAPEUTICS LIMITED (GB) 2023-12-28 WO disclosed