Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 20/20 | 0.70 |
| ▸ | ATM | Q13315 | 10/20 | 0.70 |
| ▸ | ATR | Q13535 | 15/20 | 0.64 |
| ▸ | ATRIP | Q8WXE1 | 15/20 | 0.64 |
| ▸ | PIK3CB | P42338 | 16/20 | 0.60 |
| ▸ | MTOR | P42345 | 5/20 | 0.57 |
| ▸ | SERPINA2 | P20848 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21541856 | 1.00 | PRKDC (0.70) | PRKDCATMATRATRIPPIK3CB | |
| SCHEMBL21541798 | 0.88 | PRKDC (0.64) | PRKDCATMATRATRIPPIK3CB | |
| SCHEMBL21541879 | 0.86 | PRKDC (0.81) | PRKDCATMATRATRIPPIK3CB | |
| SCHEMBL30359521 | 0.86 | PRKDC (0.81) | PRKDCATMATRATRIPPIK3CB | |
| SCHEMBL21541822 | 0.86 | PRKDC (0.72) | PRKDCATMATRATRIPPIK3CB | |
| SCHEMBL21541855 | 0.83 | PRKDC (0.82) | PRKDCATMATRATRIPPIK3CB | |
| SCHEMBL21541760 | 0.83 | PRKDC (0.73) | PRKDCATMATRATRIPPIK3CB | |
| SCHEMBL30359505 | 0.82 | PRKDC (1.00) | PRKDCATMATRATRIPPIK3CB | |
| SCHEMBL21541772 | 0.81 | PRKDC (0.77) | PRKDCATMATRATRIPPIK3CB | |
| SCHEMBL21541758 | 0.80 | PRKDC (0.64) | PRKDCATMATRATRIPPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567041-B1 | SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF | IMPACT THERAPEUTICS SHANGHAI INC (CN) | 2023-12-27 | — | — | EP | disclosed |