Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 3/20 | 0.54 |
| ▸ | CES1 | P23141 | 3/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.52 |
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | PPARD | Q03181 | 7/20 | 0.52 |
| ▸ | PPARA | Q07869 | 7/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8111017 | 1.00 | HAO1 (0.63) | HAO1KMT2AMAPTCES2CES1 | |
| SCHEMBL8132087 | 1.00 | HAO1 (0.63) | HAO1KMT2AMAPTCES2CES1 | |
| SCHEMBL17919122 | 1.00 | HAO1 (0.63) | HAO1KMT2AMAPTCES2CES1 | |
| SCHEMBL5271811 | 1.00 | HAO1 (0.63) | HAO1KMT2AMAPTCES2CES1 | |
| SCHEMBL572968 | 0.98 | HAO1 (0.59) | HAO1KMT2AMAPTCES2CES1 | |
| Bromide SCHEMBL31482536 | 0.95 | HAO1 (0.57) | HAO1KMT2AMAPTCES2CES1 | |
| SCHEMBL23437862 | 0.93 | HAO1 (0.71) | HAO1KMT2AMAPTCES2CES1 | |
| SCHEMBL1914743 | 0.93 | HAO1 (0.71) | HAO1KMT2AMAPTCES2CES1 | |
| SCHEMBL7760601 | 0.93 | HAO1 (0.71) | HAO1KMT2AMAPTCES2CES1 | |
| SCHEMBL11673566 | 0.93 | HAO1 (0.71) | HAO1KMT2AMAPTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023250513-A1 | 13-MEMBERED MACROLIDE COMPOUNDS FOR TREATING DISEASES MEDIATED BY ABNORMAL PROTEIN TRANSLATION | ZIKANI THERAPEUTICS, INC. (US) | 2023-12-28 | — | — | WO | disclosed |