Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19995751 | 0.94 | MEN1 (0.49) | MEN1KMT2ASYKHTTKDM1A | |
| SCHEMBL3273406 | 0.92 | KDM1A (0.47) | MEN1KMT2ASYKHTTKDM1A | |
| SCHEMBL25231274 | 0.91 | SYK (0.47) | MEN1KMT2ASYKHTTBACE1 | |
| SCHEMBL15054425 | 0.88 | MEN1 (0.45) | MEN1KMT2ASYKHTTBACE1 | |
| SCHEMBL1446859 | 0.86 | MEN1 (0.48) | MEN1KMT2ASYKHTTBACE1 | |
| SCHEMBL4780264 | 0.85 | NPFFR1 (0.48) | MEN1KMT2ASYKHTTBACE1 | |
| SCHEMBL4780268 | 0.85 | NPFFR1 (0.48) | MEN1KMT2ASYKHTTBACE1 | |
| SCHEMBL6636967 | 0.85 | MEN1 (0.49) | MEN1KMT2ASYKHTTBACE1 | |
| SCHEMBL25447134 | 0.85 | MEN1 (0.49) | MEN1KMT2AHTTKDM1ATACR1 | |
| SCHEMBL5352770 | 0.85 | KDM1A (0.53) | MEN1KMT2ASYKHTTKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023250513-A1 | 13-MEMBERED MACROLIDE COMPOUNDS FOR TREATING DISEASES MEDIATED BY ABNORMAL PROTEIN TRANSLATION | ZIKANI THERAPEUTICS, INC. (US) | 2023-12-28 | — | — | WO | disclosed |