SCHEMBL30690374

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)[C@@H](C)O)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	8/20	0.54

▸	GRPR	P30550	3/20	0.54

▸	RXFP1	Q9HBX9	3/20	0.54

▸	MAGI3	Q5TCQ9	1/20	0.52

▸	PRMT1	Q99873	1/20	0.51

▸	PCSK9	Q8NBP7	1/20	0.50

▸	ECE1	P42892	1/20	0.50

▸	MUS81	Q96NY9	1/20	0.50

▸	EDNRA	P25101	1/20	0.49

▸	NPBWR1	P48145	2/20	0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30690361	1.00	GLP1R (0.54)	GLP1RGRPRRXFP1MAGI3PRMT1
SCHEMBL30690366	0.96	GRPR (0.55)	GLP1RGRPRRXFP1MAGI3PRMT1
SCHEMBL29443913	0.94	RXFP1 (0.54)	GLP1RGRPRRXFP1MAGI3PRMT1
SCHEMBL30690371	0.93	PCSK9 (0.54)	GLP1RGRPRRXFP1MAGI3PCSK9
SCHEMBL29443915	0.88	GLP1R (0.64)	GLP1RRXFP1MAGI3ECE1MUS81
SCHEMBL29443912	0.87	RXFP1 (0.63)	GLP1RGRPRRXFP1ECE1MUS81
SCHEMBL29742991	0.87	EDNRA (0.54)	GLP1RGRPRRXFP1MAGI3PRMT1
SCHEMBL31045764	0.86	MAGI3 (0.54)	GLP1RGRPRMAGI3PRMT1PCSK9
SCHEMBL30690390	0.86	GLP1R (0.61)	GLP1RECE1MUS81NPBWR1
SCHEMBL29443914	0.86	GLP1R (0.61)	GLP1RECE1MUS81NPBWR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-110041432-B	chimeric antigen receptor	细胞基因公司	2023-12-05	—	—	CN	disclosed