Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 14/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 14/20 | 0.45 |
| ▸ | KIT | P10721 | 5/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | WNT1 | P04628 | 13/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690501 | 1.00 | GSK3B (0.45) | GSK3BDYRK1AKITCSF1RWNT1 | |
| SCHEMBL30690666 | 0.96 | KIT (0.42) | GSK3BDYRK1AKITCSF1RWNT1 | |
| SCHEMBL30690608 | 0.95 | GSK3B (0.43) | GSK3BDYRK1AKITCSF1RWNT1 | |
| SCHEMBL30690660 | 0.93 | KIT (0.42) | GSK3BDYRK1AKITCSF1RWNT1 | |
| SCHEMBL30690513 | 0.93 | KIT (0.42) | GSK3BDYRK1AKITCSF1RWNT1 | |
| SCHEMBL30690448 | 0.93 | GSK3B (0.43) | GSK3BDYRK1AKITCSF1RWNT1 | |
| SCHEMBL30690740 | 0.93 | GSK3B (0.43) | GSK3BDYRK1AKITCSF1RWNT1 | |
| SCHEMBL30690643 | 0.92 | GSK3B (0.47) | GSK3BDYRK1AKITCSF1RWNT1 | |
| SCHEMBL30690591 | 0.91 | GSK3B (0.47) | GSK3BDYRK1AKITCSF1RWNT1 | |
| SCHEMBL30690728 | 0.90 | GSK3B (0.43) | GSK3BDYRK1AKITCSF1RWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | claimed |