Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.51 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 3/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12481069 | 0.82 | MAPK1 (0.53) | NPC1MAPK1MPONPBWR1KDM4E | |
| SCHEMBL20773519 | 0.78 | NPC1 (0.49) | NPC1MAPK1MPONPBWR1KDM4E | |
| SCHEMBL22716415 | 0.75 | NR1H2 (0.50) | NR1H2NR1H3LIPGALDH1A1KMT2A | |
| SCHEMBL21516008 | 0.74 | MAPK1 (0.51) | NPC1MAPK1MPONPBWR1KDM4E | |
| SCHEMBL20695961 | 0.74 | MAPK1 (0.51) | NPC1MAPK1MPONPBWR1KDM4E | |
| SCHEMBL18584960 | 0.74 | NPC1 (0.56) | NPC1MAPK1MPONPBWR1KDM4E | |
| SCHEMBL23139043 | 0.73 | NPC1 (0.47) | NPC1MAPK1MPONPBWR1KDM4E | |
| SCHEMBL24352674 | 0.73 | NPC1 (0.47) | NPC1MAPK1MPONPBWR1KDM4E | |
| SCHEMBL28264645 | 0.73 | HCRTR1 (0.38) | LMNA | |
| SCHEMBL3005570 | 0.73 | IDO1 (0.49) | NR1H2NR1H3LIPGMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4540258-B1 | RUTHENIUM COMPLEXES AND THEIR USES IN CHEMICAL REACTIONS | UNIV MANCHESTER (GB) | 2026-04-15 | — | — | EP | disclosed |
| US-20250242335-A1 | CATALYST | UNIV MANCHESTER (GB) | 2025-07-31 | — | — | US | disclosed |
| EP-4540258-A1 | CATALYST | The University of Manchester (GB) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023247563-A1 | CATALYST | THE UNIVERSITY OF MANCHESTER (GB) | 2023-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250242335-A1 | CATALYST | CYP1A1, CYP1A2, CYP2B6 | NR1H2 1131/4885NR1H3 1536/4885LIPG 4514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.