Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30691340 | 1.00 | MCHR1 (0.33) | MCHR1KDM1AMAOBPDE10ATRPM5 | |
| SCHEMBL30691342 | 0.84 | HRH4 (0.33) | KDM1AMAOBHRH4 | |
| SCHEMBL30691089 | 0.84 | SCN5A (0.30) | MCHR1IGF1R | |
| SCHEMBL30691153 | 0.84 | SCN5A (0.30) | MCHR1IGF1R | |
| SCHEMBL30691572 | 0.83 | KCNN1 (0.37) | HRH4 | |
| SCHEMBL30691293 | 0.83 | KCNN1 (0.37) | HRH4 | |
| SCHEMBL30691530 | 0.83 | MEN1 (0.32) | PDE10A | |
| SCHEMBL30691382 | 0.83 | MEN1 (0.32) | PDE10A | |
| SCHEMBL30691638 | 0.82 | — | — | |
| SCHEMBL30691524 | 0.82 | DPP4 (0.33) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119997954-A | Compounds for the treatment of spinocerebellar ataxia type 3 | PTC医疗公司 | 2025-05-13 | — | — | CN | claimed |
| EP-4543444-A1 | COMPOUNDS FOR TREATING SPINOCEREBELLAR ATAXIA TYPE 3 | PTC Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | claimed |
| WO-2023250316-A1 | COMPOUNDS FOR TREATING SPINOCEREBELLAR ATAXIA TYPE 3 | PTC THERAPEUTICS, INC. (US) | 2023-12-28 | — | — | WO | claimed |