Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.61 |
| ▸ | INSR | P06213 | 5/20 | 0.56 |
| ▸ | IGF1R | P08069 | 5/20 | 0.56 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.56 |
| ▸ | MET | P08581 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26906621 | 1.00 | EGFR (0.61) | EGFRINSRIGF1RALKMET | |
| SCHEMBL26906536 | 0.97 | EGFR (0.64) | EGFRINSRIGF1RALKMET | |
| SCHEMBL26906725 | 0.94 | EGFR (0.56) | EGFRINSRIGF1RALK | |
| SCHEMBL26906550 | 0.91 | EGFR (0.66) | EGFRINSRIGF1RALKMET | |
| SCHEMBL26906605 | 0.91 | EGFR (0.56) | EGFRINSRIGF1RALK | |
| SCHEMBL26906853 | 0.90 | EGFR (0.71) | EGFRINSRIGF1RALKMET | |
| SCHEMBL26906799 | 0.89 | EGFR (0.67) | EGFRINSRIGF1RALKMET | |
| SCHEMBL26906658 | 0.88 | EGFR (0.60) | EGFRINSRIGF1RALKMET | |
| SCHEMBL30692638 | 0.88 | EGFR (0.69) | EGFRINSRIGF1RALKMET | |
| SCHEMBL26906638 | 0.88 | EGFR (0.69) | EGFRINSRIGF1RALKMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4286376-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | Therapex Co., Ltd. (KR) | 2023-12-06 | — | — | EP | claimed |
| EP-4286376-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | Therapex Co., Ltd. (KR) | 2023-12-06 | — | — | EP | disclosed |