Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.56 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26906887 | 1.00 | EGFR (0.56) | EGFRALK | |
| SCHEMBL26906509 | 0.94 | EGFR (0.57) | EGFRALK | |
| SCHEMBL26906545 | 0.92 | EGFR (0.58) | EGFRALK | |
| SCHEMBL26906607 | 0.90 | EGFR (0.53) | EGFR | |
| SCHEMBL26906811 | 0.90 | EGFR (0.53) | EGFRALK | |
| SCHEMBL26906829 | 0.88 | EGFR (0.56) | EGFR | |
| SCHEMBL26906536 | 0.88 | EGFR (0.64) | EGFRALK | |
| SCHEMBL26906843 | 0.87 | EGFR (0.61) | EGFRALK | |
| SCHEMBL26906882 | 0.87 | EGFR (0.49) | EGFRALK | |
| SCHEMBL26906652 | 0.87 | EGFR (0.66) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4286376-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | Therapex Co., Ltd. (KR) | 2023-12-06 | — | — | EP | disclosed |