Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 5/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.68 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.56 |
| ▸ | CDK2 | P24941 | 1/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22584977 | 1.00 | HDAC3 (0.68) | HDAC3HDAC1MEN1KMT2AHDAC8 | |
| SCHEMBL16887473 | 0.84 | PSEN1 (0.59) | HDAC3HDAC1MEN1KMT2AHDAC8 | |
| SCHEMBL16061441 | 0.82 | HDAC3 (0.68) | HDAC3HDAC1MEN1KMT2AHDAC8 | |
| SCHEMBL15647172 | 0.79 | MEN1 (0.82) | HDAC3HDAC1MEN1KMT2AHDAC8 | |
| SCHEMBL1736045 | 0.79 | MEN1 (0.46) | HDAC3HDAC1MEN1KMT2AHDAC8 | |
| SCHEMBL1484389 | 0.78 | HDAC3 (0.60) | HDAC3HDAC1MEN1KMT2AHDAC8 | |
| SCHEMBL16879501 | 0.78 | BRAF (0.55) | MEN1KMT2AALDH1A1GAAHPGD | |
| SCHEMBL17673062 | 0.78 | MAPT (0.65) | HDAC3HDAC1MEN1KMT2AHDAC8 | |
| SCHEMBL7930779 | 0.78 | HDAC1 (0.48) | HDAC3HDAC1MEN1KMT2AHDAC8 | |
| SCHEMBL22953598 | 0.77 | HDAC3 (0.59) | HDAC3HDAC1MEN1KMT2AHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111406054-B | 1,2, 4-oxadiazole derivatives as inhibitors of histone deacetylase 6 | 奥莱松基因组股份有限公司 | 2024-01-02 | — | — | CN | disclosed |