Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 6/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1972615 | 1.00 | PDE4B (0.42) | PDE4BSTSTACR3SLC6A2SLC6A4 | |
| SCHEMBL15397556 | 0.86 | SLC6A2 (0.40) | TACR3SLC6A2SLC6A4SLC6A3TACR1 | |
| SCHEMBL1970998 | 0.83 | PDE4B (0.44) | PDE4BSTSTACR3SLC6A2SLC6A4 | |
| SCHEMBL30693130 | 0.83 | PDE4B (0.44) | PDE4BSTSTACR3SLC6A2SLC6A4 | |
| SCHEMBL13814586 | 0.81 | TACR2 (0.45) | PDE4BSTSTACR1USP30 | |
| SCHEMBL13801636 | 0.81 | TACR2 (0.45) | PDE4BSTSTACR1USP30 | |
| SCHEMBL13801243 | 0.81 | USP30 (0.50) | PDE4BSTSUSP30 | |
| SCHEMBL13801614 | 0.81 | TACR2 (0.45) | PDE4BSTSTACR1USP30 | |
| SCHEMBL13814633 | 0.81 | USP30 (0.50) | PDE4BSTSUSP30 | |
| SCHEMBL13801256 | 0.81 | TACR2 (0.45) | PDE4BSTSTACR1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49686-E1 | Nitrogen-containing heterocyclic compound and use of same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-10 | — | — | US | disclosed |