Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 18/20 | 0.51 |
| ▸ | TACR2 | P21452 | 7/20 | 0.51 |
| ▸ | TACR3 | P29371 | 5/20 | 0.49 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1973535 | 1.00 | TACR1 (0.51) | TACR1TACR2TACR3STSMEN1 | |
| SCHEMBL1973933 | 0.89 | TACR1 (0.53) | TACR1TACR2TACR3STS | |
| SCHEMBL30693175 | 0.89 | TACR1 (0.53) | TACR1TACR2TACR3STS | |
| SCHEMBL15397681 | 0.88 | TACR1 (0.54) | TACR1TACR2TACR3 | |
| SCHEMBL15397682 | 0.88 | TACR1 (0.54) | TACR1TACR2TACR3 | |
| SCHEMBL15463497 | 0.88 | TACR1 (0.54) | TACR1TACR2TACR3 | |
| SCHEMBL13801593 | 0.86 | TACR1 (0.51) | TACR1STSMEN1KMT2A | |
| SCHEMBL13814718 | 0.86 | TACR1 (0.51) | TACR1STSMEN1KMT2A | |
| SCHEMBL1968672 | 0.84 | TACR1 (0.49) | TACR1STS | |
| SCHEMBL30693218 | 0.84 | TACR1 (0.49) | TACR1STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49686-E1 | Nitrogen-containing heterocyclic compound and use of same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-10 | — | — | US | disclosed |