Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 8/20 | 0.49 |
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12513685 | 1.00 | PDE4B (0.49) | PDE4BDPP4RORCSLC6A2SLC6A4 | |
| SCHEMBL29087338 | 1.00 | PDE4B (0.49) | PDE4BDPP4RORCSLC6A2SLC6A4 | |
| SCHEMBL29994888 | 1.00 | PDE4B (0.49) | PDE4BDPP4RORCSLC6A2SLC6A4 | |
| SCHEMBL1971248 | 1.00 | PDE4B (0.49) | PDE4BDPP4RORCSLC6A2SLC6A4 | |
| SCHEMBL1968100 | 1.00 | PDE4B (0.49) | PDE4BDPP4RORCSLC6A2SLC6A4 | |
| SCHEMBL12435403 | 0.90 | SLC6A2 (0.47) | PDE4BRORCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3999857 | 0.90 | SLC6A2 (0.47) | PDE4BRORCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL528914 | 0.90 | TACR3 (0.49) | PDE4BDPP4RORCMC4RTACR3 | |
| SCHEMBL528928 | 0.90 | PDE4B (0.47) | PDE4BDPP4RORCMC4RTACR3 | |
| SCHEMBL29995310 | 0.86 | PDE4B (0.50) | PDE4BRORCSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49686-E1 | Nitrogen-containing heterocyclic compound and use of same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-10 | — | — | US | disclosed |