Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 19/20 | 0.57 |
| ▸ | TACR2 | P21452 | 11/20 | 0.57 |
| ▸ | TACR3 | P29371 | 2/20 | 0.57 |
| ▸ | TAC3 | Q9UHF0 | 2/20 | 0.54 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1972571 | 1.00 | TACR1 (0.57) | TACR1TACR2TACR3TAC3SGMS1 | |
| SCHEMBL15397541 | 0.89 | TACR1 (0.61) | TACR1TACR2TACR3TAC3 | |
| SCHEMBL1970339 | 0.85 | TACR1 (0.53) | TACR1TACR2TACR3TAC3SGMS1 | |
| SCHEMBL30693211 | 0.85 | TACR1 (0.53) | TACR1TACR2TACR3TAC3SGMS1 | |
| SCHEMBL1970538 | 0.85 | TACR1 (0.79) | TACR1TACR2TACR3TAC3 | |
| SCHEMBL30693177 | 0.84 | TACR1 (0.56) | TACR1TACR2TACR3TAC3 | |
| SCHEMBL2218821 | 0.84 | TACR1 (0.56) | TACR1TACR2TACR3TAC3 | |
| SCHEMBL1968592 | 0.82 | TACR1 (0.52) | TACR1TACR2TACR3TAC3 | |
| SCHEMBL30693203 | 0.82 | TACR1 (0.52) | TACR1TACR2TACR3TAC3 | |
| SCHEMBL1974090 | 0.82 | TACR1 (0.64) | TACR1TACR2TACR3TAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49686-E1 | Nitrogen-containing heterocyclic compound and use of same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-10 | — | — | US | disclosed |