Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 13/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TACR2 | P21452 | 7/20 | 0.42 |
| ▸ | TAC3 | Q9UHF0 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 3/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1971060 | 1.00 | TACR1 (0.47) | TACR1TP53TACR2TAC3TACR3 | |
| SCHEMBL15397629 | 0.88 | TACR1 (0.43) | TACR1TACR2TAC3TACR3 | |
| SCHEMBL1968714 | 0.85 | TACR1 (0.60) | TACR1TACR2TAC3TACR3 | |
| SCHEMBL1971144 | 0.77 | USP30 (0.51) | TACR1TP53TACR2TAC3TACR3 | |
| Hydrochloric Acid SCHEMBL1969632 | 0.77 | TACR1 (0.38) | TACR1TACR2TAC3TACR3 | |
| SCHEMBL1970339 | 0.77 | TACR1 (0.53) | TACR1TACR2TAC3TACR3 | |
| SCHEMBL30693211 | 0.77 | TACR1 (0.53) | TACR1TACR2TAC3TACR3 | |
| SCHEMBL4150434 | 0.77 | TACR1 (0.49) | TACR1TACR2TAC3TACR3STS | |
| SCHEMBL13801311 | 0.77 | TACR1 (0.49) | TACR1TACR2TAC3TACR3STS | |
| SCHEMBL13801316 | 0.77 | TACR1 (0.49) | TACR1TACR2TAC3TACR3STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49686-E1 | Nitrogen-containing heterocyclic compound and use of same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-10 | — | — | US | disclosed |