Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3069383 | 1.00 | TOP1 (0.37) | TOP1ACE2FFAR1FFAR4GABRR1 | |
| SCHEMBL6302500 | 0.98 | ACE2 (0.38) | ACE2FFAR1FFAR4GABRR1CYP1A2 | |
| SCHEMBL3270491 | 0.98 | ACE2 (0.38) | ACE2FFAR1FFAR4GABRR1CYP1A2 | |
| SCHEMBL585188 | 0.86 | F7 (0.50) | TOP1ACE2FFAR1FFAR4CYP1A2 | |
| SCHEMBL1026928 | 0.86 | F7 (0.50) | TOP1ACE2FFAR1FFAR4CYP1A2 | |
| SCHEMBL3076324 | 0.86 | F7 (0.50) | TOP1ACE2FFAR1FFAR4CYP1A2 | |
| SCHEMBL4585236 | 0.84 | GABRR1 (0.46) | ACE2GABRR1CYP1A2 | |
| SCHEMBL4585237 | 0.84 | GABRR1 (0.46) | ACE2GABRR1CYP1A2 | |
| SCHEMBL3087503 | 0.84 | PPARG (0.53) | TOP1FFAR1FFAR4CYP1A2FAAH | |
| SCHEMBL3087501 | 0.84 | PPARG (0.53) | TOP1FFAR1FFAR4CYP1A2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-PP21289-P3 | Hop plant named ‘HBC 394’ | Hop Breeding Company, L.L.C. (US) | 2010-09-14 | — | — | US | disclosed |
| US-20090193555-P1 | Hop plant named 'HBC 394' | HOP BREEDING COMPANY, LLC | 2009-07-30 | — | — | US | disclosed |