Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700884 | 0.98 | TSHR (0.52) | TSHREPHX2AKT1ALOX5OXER1 | |
| SCHEMBL3506096 | 0.98 | TSHR (0.52) | TSHREPHX2AKT1ALOX5OXER1 | |
| SCHEMBL18339165 | 0.98 | TSHR (0.52) | TSHREPHX2AKT1ALOX5OXER1 | |
| SCHEMBL2401513 | 0.89 | TSHR (0.63) | TSHREPHX2AKT1ALOX5OXER1 | |
| SCHEMBL9188658 | 0.89 | TSHR (0.63) | TSHREPHX2AKT1ALOX5OXER1 | |
| SCHEMBL2401509 | 0.89 | TSHR (0.63) | TSHREPHX2AKT1ALOX5OXER1 | |
| SCHEMBL10225392 | 0.85 | EPHX2 (0.58) | TSHREPHX2ALOX5OXER1ALDH1A1 | |
| SCHEMBL3076326 | 0.85 | EPHX2 (0.58) | TSHREPHX2ALOX5OXER1LMNA | |
| SCHEMBL11577145 | 0.85 | EPHX2 (0.58) | TSHREPHX2ALOX5OXER1LMNA | |
| SCHEMBL23706440 | 0.84 | TSHR (0.52) | TSHREPHX2AKT1ALOX5OXER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-PP21289-P3 | Hop plant named ‘HBC 394’ | Hop Breeding Company, L.L.C. (US) | 2010-09-14 | — | — | US | disclosed |
| US-20090193555-P1 | Hop plant named 'HBC 394' | HOP BREEDING COMPANY, LLC | 2009-07-30 | — | — | US | disclosed |