Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | TDO2 | P48775 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | CASP6 | P55212 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30694309 | 1.00 | POLB (0.53) | POLBALDH1A1NCOA1NCOA3MEN1 | |
| SCHEMBL30694285 | 0.79 | POLB (0.53) | POLBALDH1A1NCOA1NCOA3MEN1 | |
| SCHEMBL31067259 | 0.78 | CYP1A2 (0.65) | POLBALDH1A1NCOA1NCOA3MEN1 | |
| SCHEMBL10844067 | 0.77 | POLB (0.61) | POLBALDH1A1NCOA1NCOA3MEN1 | |
| SCHEMBL31067269 | 0.77 | POLB (0.61) | POLBALDH1A1NCOA1NCOA3MEN1 | |
| SCHEMBL7812084 | 0.75 | MAPT (0.67) | POLBALDH1A1NCOA1NCOA3MEN1 | |
| SCHEMBL358828 | 0.75 | CYP1A2 (0.65) | POLBALDH1A1NCOA1NCOA3MEN1 | |
| SCHEMBL5165997 | 0.74 | POLB (0.53) | POLBALDH1A1NCOA1NCOA3MEN1 | |
| SCHEMBL1682758 | 0.74 | MAPT (0.69) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL27242758 | 0.74 | MAPT (0.65) | POLBALDH1A1NCOA1NCOA3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023236893-A1 | USE OF NITROXOLINE COMPOUND IN ENHANCING EFFECT OF ANTIBACTERIAL AGENT | 江苏亚虹医药科技股份有限公司 | 2023-12-14 | — | — | WO | disclosed |