Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GNRHR | P30968 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29257418 | 0.88 | TDP1 (0.54) | TDP1ASAH1LMNAALDH1A1GAA | |
| SCHEMBL30423475 | 0.88 | TDP1 (0.54) | TDP1ASAH1LMNAALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL30694219 | 0.86 | TDP1 (0.53) | TDP1ASAH1LMNAALDH1A1GAA | |
| SCHEMBL15459787 | 0.77 | POLB (0.55) | TDP1POLBKDM4ECYP2D6MAPK1 | |
| SCHEMBL5989512 | 0.77 | POLB (0.64) | ASAH1ALDH1A1GAAPOLBKDM4E | |
| SCHEMBL28775906 | 0.77 | POLB (0.64) | ASAH1ALDH1A1GAAPOLBKDM4E | |
| SCHEMBL31661829 | 0.77 | POLB (0.64) | ASAH1ALDH1A1GAAPOLBKDM4E | |
| SCHEMBL9899331 | 0.77 | POLB (0.64) | ASAH1ALDH1A1GAAPOLBKDM4E | |
| SCHEMBL7395617 | 0.76 | TDP1 (0.54) | TDP1LMNAALDH1A1GAAPOLB | |
| SCHEMBL2054473 | 0.76 | TDP1 (0.51) | TDP1ALDH1A1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117229286-A | Aromatic compound, preparation method thereof and application thereof in preparation of estrogen receptor degradation agent | 海创药业股份有限公司 | 2023-12-15 | — | — | CN | disclosed |