Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19785540 | 1.00 | PTPN11 (0.39) | PTPN11KCNH2 | |
| SCHEMBL21154268 | 0.94 | PTPN11 (0.36) | PTPN11KCNH2 | |
| SCHEMBL25514412 | 0.90 | PTPN11 (0.40) | PTPN11KCNH2 | |
| SCHEMBL23425106 | 0.86 | PTPN11 (0.39) | PTPN11KCNH2 | |
| SCHEMBL21154449 | 0.83 | PTPN11 (0.37) | PTPN11KCNH2 | |
| SCHEMBL19785548 | 0.80 | PTPN11 (0.39) | PTPN11KCNH2 | |
| SCHEMBL30295976 | 0.79 | PTPN11 (0.40) | PTPN11KCNH2 | |
| SCHEMBL19785255 | 0.79 | PTPN11 (0.40) | PTPN11KCNH2 | |
| SCHEMBL25514418 | 0.78 | PTPN11 (0.39) | PTPN11KCNH2 | |
| SCHEMBL23186823 | 0.78 | PTPN11 (0.36) | PTPN11KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484856-B1 | 2,5-DISUBSTITUTED 3-METHYL PYRAZINES AND 2,5,6-TRISUBSTITUTED 3-METHYL PYRAZINES AS ALLOSTERIC SHP2 INHIBITORS | REVOLUTION MEDICINES INC (US) | 2023-11-15 | — | — | EP | disclosed |