Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 2/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | LTK | P29376 | 1/20 | 0.32 |
| ▸ | GRK5 | P34947 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27081772 | 1.00 | PTGER4 (0.33) | PTGER4CDK8AURKADAPK3JAK2 | |
| SCHEMBL29839778 | 0.79 | PTGER4 (0.36) | PTGER4CDK8GSK3AGSK3BAXL | |
| SCHEMBL1600681 | 0.79 | PTGER4 (0.36) | PTGER4CDK8GSK3AGSK3BAXL | |
| SCHEMBL15650331 | 0.74 | GSK3A (0.37) | PTGER4GSK3AGSK3B | |
| SCHEMBL1593590 | 0.73 | JAK2 (0.37) | CDK8AURKADAPK3JAK2PRKD3 | |
| SCHEMBL30370204 | 0.73 | JAK2 (0.39) | CDK8AURKADAPK3JAK2PRKD3 | |
| SCHEMBL22582235 | 0.73 | JAK2 (0.39) | CDK8AURKADAPK3JAK2PRKD3 | |
| SCHEMBL30242908 | 0.73 | GRM4 (0.32) | CDK8AURKADAPK3JAK2PRKD3 | |
| SCHEMBL14685108 | 0.73 | GRM4 (0.32) | CDK8AURKADAPK3JAK2PRKD3 | |
| SCHEMBL29806235 | 0.73 | JAK2 (0.37) | CDK8AURKADAPK3JAK2PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313972-B1 | INDOLINE DERIVATIVES AS DDRS INHIBITORS | CHIESI FARM SPA (IT) | 2025-01-29 | — | — | EP | disclosed |
| CN-117062812-A | Indoline derivatives as DDR inhibitors | 奇斯药制品公司 | 2023-11-14 | — | — | CN | disclosed |