Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CETP | P11597 | 4/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2469341 | 0.89 | TSHR (0.56) | TSHRCETPLTA4HEPHX2SRC | |
| SCHEMBL30697402 | 0.85 | TSHR (0.55) | TSHRCETPLTA4HEPHX2SRC | |
| SCHEMBL5028595 | 0.80 | TSHR (0.60) | TSHRCETPSRCPDPK1MTOR | |
| SCHEMBL51153 | 0.76 | TSHR (0.52) | TSHR | |
| SCHEMBL4839007 | 0.74 | TSHR (0.53) | TSHRCETPFOLH1 | |
| SCHEMBL28006880 | 0.74 | TSHR (0.50) | TSHRPDPK1MTOR | |
| SCHEMBL15021274 | 0.74 | TSHR (0.50) | TSHR | |
| Hydrochloric Acid SCHEMBL27474797 | 0.74 | TSHR (0.50) | TSHR | |
| SCHEMBL11148077 | 0.73 | TSHR (0.52) | TSHRCETPSRCPDPK1MTOR | |
| SCHEMBL3360553 | 0.73 | TSHR (0.52) | TSHRCETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543893-A1 | N-SUBSTITUTED INDOLE DERIVATIVES AND CONJUGATES FOR THE TREATMENT OF CANCER | Evexta Bio (FR) | 2025-04-30 | — | — | EP | disclosed |
| WO-2024003002-A1 | N-SUBSTITUTED INDOLE DERIVATIVES AND CONJUGATES FOR THE TREATMENT OF CANCER | DIACCURATE (FR) | 2024-01-04 | — | — | WO | disclosed |