Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 16/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23635834 | 1.00 | STING1 (0.72) | STING1KDM4EALDH1A1GLAGAA | |
| SCHEMBL23111967 | 0.88 | STING1 (0.79) | STING1KDM4EALDH1A1GLAGAA | |
| SCHEMBL23630826 | 0.87 | STING1 (0.72) | STING1KDM4EALDH1A1GLAGAA | |
| SCHEMBL23635929 | 0.87 | STING1 (0.70) | STING1KDM4EALDH1A1GLAGAA | |
| SCHEMBL30697679 | 0.86 | STING1 (0.72) | STING1KDM4EALDH1A1GLAGAA | |
| SCHEMBL23635898 | 0.86 | STING1 (0.72) | STING1KDM4EALDH1A1GLAGAA | |
| SCHEMBL25853696 | 0.85 | STING1 (0.62) | STING1ALOX5APFEN1 | |
| SCHEMBL23630819 | 0.84 | STING1 (1.00) | STING1ALOX5APFEN1 | |
| SCHEMBL23630801 | 0.78 | STING1 (0.69) | STING1 | |
| SCHEMBL23630774 | 0.78 | STING1 (0.69) | STING1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793988-B1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | CTXT PTY LTD (AU) | 2023-11-15 | — | — | EP | disclosed |