Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 15/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23635868 | 1.00 | STING1 (0.64) | STING1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL23635864 | 0.92 | STING1 (0.77) | STING1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL23635903 | 0.92 | STING1 (0.77) | STING1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL23635865 | 0.86 | STING1 (0.47) | STING1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL30697676 | 0.86 | STING1 (0.47) | STING1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL23630832 | 0.86 | STING1 (0.84) | STING1 | |
| SCHEMBL23112016 | 0.86 | STING1 (0.68) | STING1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL23112039 | 0.85 | STING1 (0.81) | STING1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL23635858 | 0.85 | STING1 (0.63) | STING1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL23111978 | 0.84 | STING1 (0.78) | STING1ALDH1A1HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793988-B1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | CTXT PTY LTD (AU) | 2023-11-15 | — | — | EP | disclosed |