Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 13/20 | 0.47 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27038569 | 1.00 | MDM2 (0.49) | MDM2NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL30698933 | 0.86 | ABL1 (0.48) | ABL1MAP4K1GSK3B | |
| SCHEMBL27037106 | 0.86 | ABL1 (0.48) | ABL1MAP4K1GSK3B | |
| SCHEMBL27037878 | 0.85 | MAP4K1 (0.44) | ABL1MAP4K1GSK3B | |
| SCHEMBL27037502 | 0.85 | MAP4K1 (0.44) | ABL1MAP4K1GSK3B | |
| SCHEMBL30698592 | 0.85 | MAP4K1 (0.44) | ABL1MAP4K1GSK3B | |
| SCHEMBL27037904 | 0.85 | MAP4K1 (0.44) | ABL1MAP4K1GSK3B | |
| SCHEMBL30699000 | 0.85 | GSK3B (0.44) | ABL1MAP4K1GSK3BMAPT | |
| SCHEMBL30698913 | 0.85 | ABL1 (0.47) | ABL1MAP4K1GSK3BMAPT | |
| SCHEMBL27037988 | 0.85 | GSK3B (0.44) | ABL1MAP4K1GSK3BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4539840-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | Neuron23, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| CN-119730846-A | Kinase modulators and methods of use thereof | 神经元23公司 | 2025-03-28 | — | — | CN | disclosed |
| WO-2023244788-A9 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2024-09-12 | — | — | WO | disclosed |
| WO-2023244788-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2023-12-21 | — | — | WO | disclosed |