Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 4/20 | 0.53 |
| ▸ | ABL1 | P00519 | 14/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30699125 | 1.00 | MAP4K1 (0.53) | MAP4K1ABL1GSK3BJAK2TYK2 | |
| SCHEMBL30698984 | 0.91 | MAP4K1 (0.56) | MAP4K1ABL1GSK3BJAK2TYK2 | |
| SCHEMBL27037322 | 0.91 | MAP4K1 (0.56) | MAP4K1ABL1GSK3BJAK2TYK2 | |
| SCHEMBL30698997 | 0.87 | MAP4K1 (0.52) | MAP4K1ABL1TYK2 | |
| SCHEMBL30698569 | 0.86 | MAP4K1 (0.53) | MAP4K1ABL1 | |
| SCHEMBL27037564 | 0.83 | MAP4K1 (0.56) | MAP4K1ABL1 | |
| SCHEMBL30699133 | 0.83 | MAP4K1 (0.56) | MAP4K1ABL1 | |
| SCHEMBL27072155 | 0.81 | MAP4K1 (0.53) | MAP4K1ABL1GSK3BJAK2TYK2 | |
| SCHEMBL30698801 | 0.80 | MAP4K1 (0.60) | MAP4K1ABL1GSK3B | |
| SCHEMBL27037613 | 0.80 | MAP4K1 (0.60) | MAP4K1ABL1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4539840-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | Neuron23, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023244788-A9 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2024-09-12 | — | — | WO | disclosed |
| WO-2023244788-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2023-12-21 | — | — | WO | disclosed |