Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30706745 | 0.88 | KRAS (0.33) | KRAS | |
| SCHEMBL29936919 | 0.78 | KRAS (0.46) | KRAS | |
| Hydrochloric Acid SCHEMBL30699364 | 0.77 | KRAS (0.46) | KRAS | |
| SCHEMBL30391380 | 0.72 | KRAS (0.42) | KRAS | |
| SCHEMBL30706774 | 0.71 | KRAS (0.41) | KRAS | |
| SCHEMBL30706980 | 0.71 | KRAS (0.41) | KRAS | |
| SCHEMBL25336421 | 0.70 | KRAS (0.39) | KRAS | |
| SCHEMBL26288684 | 0.69 | — | — | |
| SCHEMBL24272822 | 0.69 | — | — | |
| SCHEMBL27269373 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244713-A1 | QUINAZOLINE DERIVATIVES, COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |