Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728519 | 0.85 | HSD17B10 (0.42) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL7763657 | 0.81 | CA1 (0.45) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL3300050 | 0.79 | KMT2A (0.40) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL203637 | 0.78 | MEN1 (0.44) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL29411714 | 0.78 | MEN1 (0.44) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL30805785 | 0.76 | KMT2A (0.43) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL27302869 | 0.76 | KMT2A (0.43) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL27302899 | 0.75 | HSD17B10 (0.50) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL27303319 | 0.75 | KMT2A (0.44) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL13469364 | 0.75 | CA1 (0.50) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244713-A1 | QUINAZOLINE DERIVATIVES, COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |