Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 8/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL610130 | 1.00 | NR1H2 (0.55) | NR1H2SRCCHRM2CHRM1CHRM3 | |
| SCHEMBL261611 | 1.00 | NR1H2 (0.55) | NR1H2SRCCHRM2CHRM1CHRM3 | |
| SCHEMBL16584744 | 1.00 | NR1H2 (0.55) | NR1H2SRCCHRM2CHRM1CHRM3 | |
| SCHEMBL19390033 | 1.00 | NR1H2 (0.55) | NR1H2SRCCHRM2CHRM1CHRM3 | |
| SCHEMBL13336742 | 1.00 | NR1H2 (0.55) | NR1H2SRCCHRM2CHRM1CHRM3 | |
| SCHEMBL29007981 | 0.90 | NR1H2 (0.51) | NR1H2SRCCHRM2CHRM1CHRM3 | |
| SCHEMBL29035448 | 0.90 | NR1H2 (0.51) | NR1H2SRCCHRM2CHRM1CHRM3 | |
| SCHEMBL10145418 | 0.88 | NR1H2 (0.49) | NR1H2SRCCHRM2CHRM1CHRM3 | |
| SCHEMBL608492 | 0.88 | NR1H2 (0.49) | NR1H2SRCCHRM2CHRM1CHRM3 | |
| SCHEMBL610842 | 0.88 | NR1H2 (0.49) | NR1H2SRCCHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3533797-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2023-12-20 | — | — | EP | disclosed |