Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609346 | 1.00 | NR1H2 (0.48) | NR1H2CHRM2CHRM1CHRM3JAK2 | |
| SCHEMBL24909283 | 1.00 | NR1H2 (0.48) | NR1H2CHRM2CHRM1CHRM3JAK2 | |
| SCHEMBL609610 | 1.00 | NR1H2 (0.48) | NR1H2CHRM2CHRM1CHRM3JAK2 | |
| SCHEMBL16584672 | 1.00 | NR1H2 (0.48) | NR1H2CHRM2CHRM1CHRM3JAK2 | |
| SCHEMBL17097458 | 0.90 | NR1H2 (0.44) | NR1H2CHRM2CHRM1CHRM3JAK2 | |
| SCHEMBL17098157 | 0.90 | NR1H2 (0.44) | NR1H2CHRM2CHRM1CHRM3JAK2 | |
| SCHEMBL17097460 | 0.90 | NR1H2 (0.44) | NR1H2CHRM2CHRM1CHRM3JAK2 | |
| SCHEMBL17056975 | 0.90 | NR1H2 (0.44) | NR1H2CHRM2CHRM1CHRM3JAK2 | |
| SCHEMBL10145613 | 0.86 | NR1H2 (0.43) | NR1H2CHRM2CHRM1CHRM3JAK2 | |
| SCHEMBL609152 | 0.86 | NR1H2 (0.43) | NR1H2CHRM2CHRM1CHRM3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3533797-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2023-12-20 | — | — | EP | disclosed |