Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.47 |
| ▸ | HTR2C | P28335 | 6/20 | 0.47 |
| ▸ | HTR2B | P41595 | 6/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23105269 | 1.00 | SLC6A4 (0.47) | SLC6A4HTR2CHTR2BHTR2ACHRNB2 | |
| Trifluoroacetic Acid SCHEMBL23091806 | 0.91 | SLC6A4 (0.44) | SLC6A4HTR2CHTR2BHTR2ACHRNB2 | |
| Trifluoroacetic Acid SCHEMBL30013426 | 0.91 | SLC6A4 (0.44) | SLC6A4HTR2CHTR2BHTR2ACHRNB2 | |
| SCHEMBL22283606 | 0.81 | SLC6A4 (0.39) | SLC6A4HTR2CHTR2BHTR2ACHRNB2 | |
| SCHEMBL22283580 | 0.81 | PDE2A (0.41) | SLC6A4HTR2CHTR2BHTR2ASCN8A | |
| SCHEMBL22283579 | 0.81 | PDE2A (0.41) | SLC6A4HTR2CHTR2BHTR2ASCN8A | |
| SCHEMBL31071547 | 0.79 | HTR2C (0.49) | SLC6A4HTR2CHTR2BHTR6 | |
| SCHEMBL22283675 | 0.77 | SLC6A4 (0.39) | SLC6A4HTR2CHTR2BHTR2ASCN8A | |
| SCHEMBL23105359 | 0.77 | IDO1 (0.50) | SLC6A4HTR2CHTR2BCHRNB2CHRNA4 | |
| SCHEMBL27149063 | 0.77 | GRIN2B (0.45) | SCN8ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |