Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 13/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30701802 | 0.88 | ALDH2 (0.75) | ALDH2GAAKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL29106378 | 0.88 | ALDH2 (0.75) | ALDH2GAAKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL29106415 | 0.86 | ALDH2 (0.78) | ALDH2GAAKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL30701810 | 0.86 | ALDH2 (0.78) | ALDH2GAAKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL30701820 | 0.85 | ALDH2 (0.71) | ALDH2GAAKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL29106315 | 0.85 | ALDH2 (0.71) | ALDH2GAAKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL29106345 | 0.85 | ALDH2 (0.81) | ALDH2GAAKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL29106343 | 0.85 | ALDH2 (0.75) | ALDH2GAAKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL29106340 | 0.83 | ALDH2 (0.79) | ALDH2GAAKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL29106356 | 0.83 | ALDH2 (0.79) | ALDH2GAAKDM4EHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109942537-B | ALDH2 agonist, preparation method and application thereof | 中国人民解放军第二军医大学 | 2023-11-17 | — | — | CN | claimed |