Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.34 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.31 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27191903 | 1.00 | HAVCR2 (0.34) | HAVCR2EGLN3BRD4BRD2BRD3 | |
| SCHEMBL31341472 | 0.89 | HTT (0.34) | HAVCR2HTT | |
| SCHEMBL27192065 | 0.87 | EGLN3 (0.33) | HAVCR2EGLN3KDM4EALDH1A1HPGD | |
| SCHEMBL27191885 | 0.87 | HAVCR2 (0.31) | HAVCR2EGLN3HTT | |
| SCHEMBL27191940 | 0.87 | HAVCR2 (0.34) | HAVCR2EGLN3BRD4BRD2BRD3 | |
| SCHEMBL27191862 | 0.86 | HAVCR2 (0.35) | HAVCR2EGLN3BRD4BRD2BRD3 | |
| SCHEMBL27192256 | 0.86 | EGLN3 (0.37) | HAVCR2EGLN3BRD4BRD2BRD3 | |
| SCHEMBL27192107 | 0.86 | HAVCR2 (0.30) | HAVCR2 | |
| SCHEMBL27191992 | 0.86 | EGLN3 (0.35) | HAVCR2EGLN3BRD4BRD2BRD3 | |
| SCHEMBL27191892 | 0.86 | EGLN3 (0.32) | HAVCR2EGLN3BRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565574-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2025-06-11 | — | — | EP | disclosed |
| CN-119731159-A | SARS-CoV2 main proteinase inhibitor | 吉利德科学公司 | 2025-03-28 | — | — | CN | disclosed |
| WO-2024031089-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-08 | — | — | WO | disclosed |